I have a client right now who has a VERY odd layout in a secondary bathroom. Although the layout allowed them to have a bathtub, it really makes the flow of the room non-functional. They are going to take out the tub and put in a shower. Since they have a bathtub in another bathroom I think it is a good idea. If you are struggling with a poor bathroom layout read this article in Houzz to get some guidelines for a remodel.
Nature and Sustainability Series at Mt. Helix Park